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Tauroursodeoxycholic acid (TUDCA) ntụ (14605-22-2)

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SKU: 14605-22-2. Category:

AASraw di na mkpoputa na ikike imeputa site na gram ruo uka nke Tauroursodeoxycholic acid (TUDCA) Powder (14605-22-2), n'okpuru usoro iwu CGMP na usoro njikwa mma.

Product Description

Tauroursodeoxycholic acid (TUDCA) Powder (14605-22-2) vidiyo


Tauroursodeoxycholic acid (TUDCA) ntụ (14605-22-2) Specification:

Ngwurugwu Chemical: Product Name: Tauroursodeoxycholic acid (TUDCA)
Cas Mba: 14605-22-2
molekụla Formula: C26H45NO6S
molekụla arọ: 499.7
Synonyms:Tauroursodeoxycholic acid, TUDCA, Tauroursodeoxycholate, Taurolite
nchekwa: Chekwaa na -20 Celsius C n’ebe ìhè na mmiri dị.
Akwụkwọ edemede (COA & HPLC wdg): Dị

Tauroursodeoxycholic acid (TUDCA) ntụ (14605-22-2) Daha:

Ọgwụ China ejirila ihe ụmụ anụmanụ mee ihe ruo ọtụtụ narị afọ dịka ọgwụ iji gwọọ ọrịa ọrịa "okpomoku". Ejiri ya mee ihe iji belata nza, belata ahụ ọkụ, ma meziwanye ịdị nkọ. Site n'okike, ejiri Bileli mee ya site na cholesterol, nke mejupụtara ogige gụnyere taurochenodeoxycholic acid, ursodeoxycholic acid, na chenodeoxycholic acid.Ihe o mere, UDCA na TUDCA bu ụzọ wee mebe ya na 1954 na Japan.

Tauroursodeoxycholic acid ntụ ntụ bụ bile acid taurine conjugate sitere na ursoodeoxycholic acid. O nwere ọrụ dị ka metabolite mmadụ, onye na-egbochi mbufụt, onye na-elekọta neuroprotective, apoptosis inhibitor, onye na-ahụ maka ọrịa obi na onye na-echekwa nkwụghachi nke ọkpụkpụ. O sitere na ursodeoxycholic acid. Ọ bụ conjugate acid nke tauroursodeoxycholate.

Tauroursodeoxycholic Acid (TUDCA) bụ ihe enyemaka imeju ewepụtara dịka ThermoLife mepụtara na ngwaahịa ha bụ Long Longer. Ọ dị ka ezigbo akụ maka igbochi cholestasis, otu n'ime ihe ọghọm dị na steroid 17 alkylated stereị. Tauroursodeoxycholic Acid (TUDCA) bụ acid nke ambiphilic bile. Ọ bụ ụdị tarsine conjugate nke ursodeoxycholic acid (UDCA). Achọpụtara ụmụ mmadụ nwere ọnụọgụ dị iche iche nke TUDCA. Agbanyeghị, bea nwere nnukwu TUDCA n'ụdị ha. TUDCA nwere mbelata mmetụta apoptotic, na-enyere aka na ọrụ gbasara obi, ọrịa Huntington, Ọrịa Parkinson, na ọrịa strok. N’oge na-adịbeghị anya, a chọpụtara na TUDCA nwere mmetụta nchebe na anya, ọkachasị gbasara nsogbu azụ azụ.

Ntughari:

  • Oveson BC, Iwase T, Hackett SF, Lee SY, Usui S, Sedlak TW, Snyder SH, Campochiaro PA, Sung JU (2011). "Ihe nke bile, bilirubin na TUDCA, na-egbochi ihe mmekpa ahụ na-akpata mkpụzụ azụ. J. Neurochem. 116 (1): 144–153. doi: 10.1111 / j.1471-4159.2010.07092.x. PMC 4083853. PMID 21054389.
  • Duan, WJ, Zhang, FK, Ou XJ, Zhang, T, Wang, XM, Wang, Y, Cui, Y, Zhao, XY, Jia, JD (2011). “[Ihe profaịlụ nke ọrịa biliary cirrhosis nke mbụ na azịza banyere mmiri ọgwụ na-egbu ursodeoxycholic acid]”. Zhonghua Gan Zang Bing Za Zhi. 19 (2): 118-120. doi: 10.3760 / cma.j.issn.1007-3418.2011.02.011 (anaghị arụ ọrụ 2019-08-20). PMID 21492515.
  • Woo SJ, Kim JH, Yu HG (2010). "Ursodeoxycholic acid na tauroursodeoxycholic acid na-ebelata choroalal neovascularization n'ụdị oke bekee nke laser." J Ocul Pharmacol Ther. 26 (3): 223–229. doi: 10.1089 / jop.2010.0012. PMID 20565307.

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