Lorcaserin HCL ntụ ntụ

Lorcaserin hydrochloride Powder Video-AASraw

Ihe odide ndị bụ isi nke Raw Lorcaserin hydrochloride

Kedu is Lorcaserin hydrochloride ntụ ntụ?

Lorcaserin hydrochloride bụ hydrochloride nke enwetara site na mmeghachi omume nke lorcaserin na otu hydrochloric acid. Ejiri ya dị ka ọgwụ mgbochi oke ibu. Ọ nwere ọrụ dị ka agonist serotonergic na agụụ nkụda mmụọ.

Lorcaserin hydrochloride ntụ ntụ na-emetụta akara kemịkalụ na ụbụrụ nke na-achịkwa agụụ. Lorcaserin HCL ntụ ntụ na-arụ ọrụ site n'inyere gị aka inwe mmetụta zuru oke na obere nri.Lorcaserin hydrochloride ntụ ntụ na-eji ya na nri na mmega ahụ iji na-emeso oke ibu. .

Kedu ihe Lorcaserin hydrochloride dị mma maka?

A na-eji Lorcaserin hydrochloride enyere ndị okenye aka ibu ma ọ bụ buru oke ibu ma nwee nsogbu ahụike metụtara ibu ka ha ghara ibu ibu ma ghara ibughachi ibu ahụ. A ghaghị iji Lorcaserin mee ihe yana nri calorie belatara na atụmatụ mmega ahụ. Lorcaserin nọ na klas ọgwụ a na-akpọ agonists ndị na-anabata serotonin. Ọ na-arụ ọrụ site n'ịbawanye mmetụta nke afọ ojuju nke mere na a na-eri obere nri.

A na-eji Lorcaserin hydrochloride yana nri obere kalori na mgbatị ahụ kwesịrị ekwesị iji nyere gị aka ịkwụsị ibu. A na-ejikwa ya na ndị buru ibu nwere ike ịnwe ọrịa shuga, ọbara mgbali elu, cholesterol dị elu, ma ọ bụ ọrịa obi.

The Uru Lorcaserin hydrochloride

Lorcaserin hydrochloride bụ ọgwụ a na-enye n'ọnụ nke na-akwalite mbelata ibu. A na-eji ya na nri na mmega ahụ na ndị okenye buru ibu nwere nsogbu ahụike metụtara ibu ma ọ bụ ndị okenye buru ibu iji felata ma wepụ ya.

Lorcaserin hydrochloride bụ serotonin 2C (5-HT2C) agonist nnabata. A na-eche na lorcaserin na-ahọrọ na-akpali ndị na-anabata 5-HT2C na hypothalamus, mpaghara ụbụrụ mara na ọ na-ekere òkè dị ukwuu n'ịchịkwa agụụ na oriri. Site n'ịgbalite ndị na-anabata ndị a, lorcaserin nwere ike ibelata oriri nri site n'ịbelata agụụ na ime ka mmadụ nwee afọ ojuju ọbụna mgbe o risịrị nri dị ntakịrị karịa ka ọ dị na mbụ.

Lorcaserin hydrochloride bụ serotonin 2C agonist receptor egosiputara maka ọgwụgwọ nke njikwa ibu na-adịghị ala ala na ndị okenye nwere ọnụọgụ anụ ahụ (BMI) nke 30 ma ọ bụ karịa (obese) dị ka mgbakwunye na nri na mmega ahụ belatara calorie. A kwadoro lorcaserin maka ndị okenye nwere BMI nke 27 ma ọ bụ karịa (oke ibu) na ndị nwere ma ọ dịkarịa ala otu ọnọdụ metụtara ịdị arọ dị ka ọbara mgbali elu (ọbara mgbali elu), ụdị ọrịa shuga 2, ma ọ bụ cholesterol dị elu (dyslipidemia).

Lorcaserin hydrochloride eji dị ka ọgwụ mgbochi oke ibu

Oke ibu bụ isi mkpa ahụike na-achọ atụmatụ dị mma ma dị irè iji gboo ọrịa oke ibu. Lorcaserin bụ agonist serotonergic kpọmkwem maka onye na-anabata 5HT-2C kwadoro maka nlekọta na-adịghị ala ala nke oke ibu na ndị ọrịa nwere BMI ≥ 30 kg / m (2) ma ọ bụ BMI ≥ 27 kg / m (2) nwere nsogbu metụtara oke ibu.

Lorcaserin bụ agonist serotonergic pụrụ iche nke e mere iji belata ihe egwu metụtara ndị nnọchite mbụ na klaasị a. N'oge usoro ọgwụgwọ, a na-anabata ya nke ọma ma na-ewepụta oke ibu mana ọ bara uru nke ukwuu yana mmụba dị ukwuu na paramita cardiometabolic. Ekwesịrị ịtụle ịdị irè ọgwụgwọ na izu 12 (≥ 5% oke ibu) iji chọpụta ndị na-azaghachi ga-enweta oke oke ibu na uru metabolic site na ọgwụgwọ ogologo oge. Nsonaazụ nke ule na-aga n'ihu nke ọrịa obi (CAMELLIA TIMI 61) ga-ekpebi ọrụ lorcaserin na mgbochi mbụ nke ọrịa shuga na oke ibu / oke ibu na iji ya mee ihe na ọnụ ọgụgụ dị elu nke ndị ọrịa nwere ọrịa obi ma ọ bụ ọtụtụ ihe ize ndụ nke obi.

Ebe ịzụta Lorcaserin hydrochloride ntụ ntụ?

A na-eji Lorcaserin nyere ndị okenye aka ma ọ bụ ndị buru oke ibu ma nwee nsogbu ahụike metụtara ibu ka ha ghara ibu ibu ma ghara ịmaliteghachi ibu ahụ. A ghaghị iji Lorcaserin mee ihe yana nri calorie belatara na atụmatụ mmega ahụ. Lorcaserin nọ na klas ọgwụ a na-akpọ agonists ndị na-anabata serotonin. Ọ na-arụ ọrụ site n'ịbawanye mmetụta nke afọ ojuju nke mere na a na-eri obere nri.

Raw Lorcaserin hydrochloride Powder Report-HNMR

Kedu ihe bụ HNMR na gịnị ka ụdịdị HNMR na-agwa gị? H Nuclear Magnetic Resonance (NMR) spectroscopy bụ usoro nyocha kemịkalụ ejiri na njikwa mma na nyocha maka ịchọpụta ọdịnaya na ịdị ọcha nke ihe nlele yana usoro ihe omimi ya. Dịka ọmụmaatụ, NMR nwere ike nyochaa ngwakọta nke nwere ogige ndị ama ama. Maka ogige ndị amabeghị, enwere ike iji NMR dakọtara megide ọba akwụkwọ ọpụrụiche ma ọ bụ tụnye usoro ntọala ozugbo. Ozugbo a mara usoro nhazi ahụ, enwere ike iji NMR chọpụta ngbanwe nke mkpụrụ ndụ na ngwọta yana ịmụ ihe anụ ahụ na ọkwa molekụla dị ka mgbanwe mgbanwe, mgbanwe oge, solubility, na mgbasa.

Lorcaserin hydrochloride (1431697-94-7) -COA

Lorcaserin hydrochloride (1431697-94-7) -COA

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Reference

[1] Belviq (lorcaserin hydrochloride) mbadamba [Eisai, Inc]". DailyMed. Eisai, Inc. Ọgọst 2012. Edebere site na izizi na 21 Ọktoba 2013. eweghachiri 21 Ọktoba 2013.

[2] "FDA na-arịọ ka ewepụrụ Belviq ọgwụ na-efunahụ ibu, Belviq XR (lorcaserin) n'ahịa". Nchịkwa nri na ọgwụ US (FDA). 14 Jenụwarị 2020. eweghachiri 1 Eprel 2020.

[3] "FDA Na nkenke: FDA na-arịọ arịrịọ afọ ofufo ịwepụ ọgwụ na-efunahụ ibu mgbe nnwale ụlọ ọgwụ gosipụtara mmụba nke ọrịa kansa". FDA. Febụwarị 13, 2020.

[4] “Belviq XR (lorcaserin hydrochloride) mbadamba ihe ewepụtara agbatị”. Nchịkwa nri na ọgwụ US (FDA). 26 Ọktoba 2016. eweghachiri 14 Jenụwarị 2020.

[5] "Ngwugwu nkwenye ọgwụ: Belviq (lorcaserin hydrochloride) Mbadamba ụrọ NDA # 022529". Nchịkwa nri na ọgwụ US (FDA). 7 Ọgọstụ 2012. eweghachiri 14 Jenụwarị 2020.

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