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2-Methoxyestradiol (362-07-2)

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SKU: 362-07-2. Category:

AASraw nọ na njikọ na ike imepụta site na gram ruo n'usoro nke 2-Methoxyestradiol (362-07-2), n'okpuru ụkpụrụ CGMP na njikwa njikwa njiri mara mma.

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Product Description

Ihe onyonyo 2-Methoxyestradiol (362-07-2)


2-Methoxyestradiol (362-07-2) Specification:

Ngwurugwu Chemical: Product Name: 2-Methoxyestradiol
Zụta 2-Methoxyestradiol (362-07-2) hplc≥98% | AASraw Cas Mba: 362-07-2
molekụla Formula: C19H26O3
molekụla arọ: 302.4
Synonyms: 2-Methoxyestradiol

362-07-2

Panzem

2-Methoxyestradiol-17beta

Hydroxyestradol 2-methyl ether

nchekwa: Akọrọ, ọchịchịrị
Akwụkwọ edemede (COA & HPLC wdg): dị

2-Methoxyestradiol (362-07-2) Daha:

methoxyestradiol ntụ ntụ, nke a makwaara dị ka 2-ME, bụ estradiol metabolite bioavasite nwere ọrụ antineoplastic nwere ike, ya mere ọ bụ angiogenesis inhibitorỌ na-arụkwa ọrụ dị ka vasodilator.

2-Methoxyestradiol na-egbochi angiogenesis site na mbenweta sel protinhelial yana ịmebata apootisi sel endothelial. Ihe nnọchianya a na-egbochi uto mkpụrụ ndụ site na ijikọ ya na tubulin, nke a na-ebute ọrụ antimitotic, na ịmalite itinye caspase n'ọrụ, na-ebute njide okirikiri na oge G2, nkesa nke DNA, na apoptosis.

Ntughari:

  • 1: Perez-Sepulveda A, Espaà ± a-Perrot PP, Norwitz ER, Illanes SE. Abolzọ metabolic metụtara na 2-methoxyestradiol njikọ yana ọrụ ha na preeclampsia. Reprod Sci. 2013 Sep; 20 (9): 1020-9. doi: 10.1177 / 1933719113477483. Epub 2013 Mar 1. Nyocha. PubIDed PMID: 23456663; PubMed Central PMCID: PMC3745713.
  • 2: Machado-Linde F, Pelegrin P, Sanchez-Ferrer ML, Leon J, Cascales P, Parrilla JJ. 2-methoxyestradiol na pathophysiology nke endometriosis: gbado anya na ike angiogenesis na ikike ọgwụgwọ. Reprod Sci. 2012 Ọkt; 19 (10): 1018-29. doi: 10.1177 / 1933719112446080. Epub 2012 Aug 8. Nyocha. PubIDed PMID: 22875846.
  • 3: Peyrat JF, Brion JD, Alami M. Synthetic 2-methoxyestradiol sitere: mmekọrịta na-arụ ọrụ. Curr Med Chem. 2012; 19 (24): 4142-56. Nyocha. PubIDed PMID: 22709003.
  • 4: Verenich S, Gerk PM. Ngwọta ọgwụgwọ ọgwụgwọ nke 2-methoxyestradiol yana nsogbu ịma aka ọgwụ ya. Mol Pharm. 2010 Disemba 6; 7 (6): 2030-9. doi: 10.1021 / mp100190f. Epub 2010 Ọkt 21. Nyocha. PubIDed PMID: 20831190; PubMed Central PMCID: PMC3059899.
  • 5: Mueck AO, Seeger H. 2-Methoxyestradiol – usoro mmụta na usoro nke ime ihe. Steroid. 2010 Ọkt; 75 (10): 625-31. doi: 10.1016 / j.steroids.2010.02.016. Epub 2010 Mar 7. Nyocha. PubIDed PMID: 20214913.

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COA

HNMR

Ezi ntụziaka

LGD3303 Ntụziaka ntụ ntụ ntụ ntụ

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