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Nootropic Pramiracetam

Gịnị Bụ Nootropic?

Okwu ahụ na-ezo aka na kemịkalụ ma ọ bụ kemịkal nwere ike ịmetụta ikike ọgụgụ isi. Ha nwere ike ịbụ nri Mmeju, ogige, ma ọ bụ ọgwụ ọgwụ. Ihe atụ nke ọgwụ ọgwụ nootropic bụ Ritalin, ihe na-akpali akpali iji agwọ ADHD ma ọ bụ Memantine, ọgwụ maka mgbaka.

Ndị na-eme ihe ọgụgụ isi iji bulie ọgụgụ isi, ihe okike, na mkpali bụ uru dị mkpa na ọnọdụ asọmpi taa. Might nwere ike ịnụ ka a na-akpọ ha "ọgwụ ọjọọ" mana ha karịrị nke ahụ.

Okwu nootropic sitere na mgbọrọgwụ Greek: "nous", nke pụtara uche, na "tropin", nke pụtara ịtụgharị ma ọ bụ gbagọrọ agbagọ (dị ka osimiri).

 

Ihe eji eme nke Nootropics

Maka ngwakọta kemịkalụ ka a ga-atụle nootropic, ọ ga-agbaso njirisi doro anya. Ke ofụri ofụri, a na-anakwere nootropic

  • Enweewanye ncheta
  • Meziwanye mmeghachi omume n'okpuru nrụgide
  • Na-echebe ụbụrụ site na mmerụ anụ ahụ ma ọ bụ kemịkal
  • Mma cortical / subcortical akara
  • Nwere obere nsị ma ọ bụ akụkụ-mmetụta

Ngwakọta sịntetik na-esote njirisi ndị a bụ nke mepụtara n'oge na-adịbeghị anya, mana ọdịnala ahụike oge ochie nke China na India na-egosi ojiji nke mmanya, ginkgo biloba, na ahịhịa ndị ọzọ maka naanị ihe ndị a.

Gịnị mere Pramiracetam ji ewu ewu?

Pramiracetam bụ akụkụ nke ezinụlọ racetam, otu ìgwè nke ogige ndị sịntetik na-ekerịta ntọala pyrrolidone. Ọgwụ dị na ezinụlọ a bụ ndị na-eme ihe ike, ncheta, na ndị na-eme ka uche dịkwuo elu.

Pramiracetam na-emetụta nnweta nke ncheta n'ụzọ ziri ezi. Nnyocha na-egosi na ọ bụ neuroprotective. N'adịghị ka ọtụtụ ọgwụ ọjọọ dị na ezinụlọ racetam, a nwalere nrụpụta ọrụ ya n'ahụ ndị okenye. A nwalere ọtụtụ ogige racetam na ndị agadi amaala.

Ọ bụ nootropic dị ike nke nwere mmetụta na-adịte aka na-ewu oge. Evidencefọdụ ihe akaebe na-egosi na ọ nwere ike inye aka na mmerụ ụbụrụ ụbụrụ.

 

Pramiracetam Description

Pramiracetam (N- [2- [di (propan-2-yl) amino] ethyl] -2- (2-oxopyrrolidin-1-yl) acetamide, CI-879, Pramistar, Neupramir, Remen) bụ abụba-soluble nootropic na racetam-klas nke ogige.

Pramiracetam (CAS) 68497-62-1) egosila na ọ dị irè na ọgwụgwọ ọrịa uche nke mmalite cerebrovascular na traumatic. Nnwale na ụmụ mmadụ nwere ncheta ncheta egosila na Pramiracetam nwere ike ime ka ncheta dịkwuo elu. Ọ bụ ezie na ọ nweghị ọmụmụ ihe na-egosi na nke a bụ ihe gbasara ụmụ okorobịa ahụike, ọtụtụ kọrọ na ha nwere mmetụta nke ncheta na ncheta dị mma. Nkọwa maka ihe kpatara Pramiracetam ji eme ka ebe nchekwa dị, bụ na o gosipụtara ịbawanye oke choline.

Scientific, Choline a precursor molecule maka neurotransmitter acetylcholine, yiri nnọọ vitamin na ọ bụ ihe dị mkpa edozi. Choline nwere ike na ụfọdụ osisi na anụmanụ akụkụ ma ọ bụ mmiri ara ehi. Inwe nri kwesịrị ekwesị ma si otú a nweta choline zuru ezu yana ịgbakwunye racetams dị ka Pramiracetam nke na-ebuwanye ibu choline, nwere ike inwe mmetụta dị mma na ebe nchekwa.

Pramiracetam bu ihe anakpo racetam mebere ka ya na ihe omimi yiri nke Piracetam nne na nna. Ebu ụzọ kee ya na 1984 maka ikike iji gbochie amnesia nke sitere na electrocution. E jiri ya tụnyere ndị ọzọ so na racetam ezinụlọ, Pramiracetam bụ obere nyocha ma nwee ihe akaebe nke uru ya na ụmụ mmadụ.

N'ime ọmụmụ ihe, Pramiracetam yiri ka ọ dị irè mgbe ewepụrụ ya obere oge tupu nwalee ya nke nwere ike ime ka ọ dị mma maka ịgbakwunye n'oge nyocha agụmakwụkwọ ma ọ bụ rụọ ọrụ kpụ ọkụ n'ọnụ ebe nchekwa nchekwa na arụmọrụ na-aba uru. Ihe omumu mmadu kwadoro echiche a ma ha enyeghi ihe omuma onu ogugu rue taa.

 

Pramiracetam Nhazi nke Action

Dị ka racetams niile, a naghị aghọtacha usoro dị n'azụ pramiracetam, ọ bụ n'ihi enweghị nnukwu nnyocha.

Agbanyeghị, ụfọdụ ọmụmụ ihe bidoro rụtụrụ aka na usoro ole na ole ndị a:

Nwere ike ịbawanye ogo acetylcholine (site na ịbawanye choline na sel site na 30-37%);

Nwere ike ime ka mmepụta nitric oxide na ụbụrụ;

▪ Enwere ike itinye homonụ adrenal dịka aldosterone na cortisol (corticosterone);

Otú ọ dị, data gbasara usoro ndị a dị n'elu na-abịa ihe fọrọ nke nta ka ọ bụrụ naanị site n'ọmụmụ anụmanụ - nke kachasị na oke na ụmụ oke - ya mere enweghi ike ime mkpebi siri ike banyere usoro ikike pramiracetam na ụbụrụ nke ndị ọrụ mmadụ dị mma.

Nootropic Pramiracetam

Pramiracetam uru

Pramiracetam bụ a ezi nootropic, kere kpọmkwem iji mee ka cognition mara. Uru na mmetụta ya gụnyere ndị a:

 

  • Nchekwa ka mma

Pramiracetam bụ ihe nkwalite nchekwa echepụtara echepụtara, nwalere ọtụtụ afọ ruo ọtụtụ iri afọ ma gosipụta ọfụma na ọmụmụ ụmụ anụmanụ‍ na ọnwụnwa ahụike nke ndị na-eto eto nwere mmetụ mmata n'ihi ụbụrụ merụrụ ahụ.

Pramiracetam na-eme ka ncheta dịkwuo mma ma na-akpali akpali hippocampus, akụkụ nke ụbụrụ bụ isi maka okike nke ncheta ọhụrụ yana site na ịme dị ka mgbochi amnesic nke na-ebelata nchefu. Ọtụtụ ndị ọrụ na-ekwupụtakwa mmụba dị ịrịba ama na icheta ọsọ, nkwupụta nke ọmụmụ ụmụ anụmanụ kwadoro

 

  • Ịbawanyewanye Ntị na Ịmụbawanye Ịmụta Ịmụta

Aha Pramiracetam dị ka nkwalite mmụcha nke na-eme ka nchekwube ma gbasaa ikike mmụta emeela ka ọ bụrụ nhọrọ kachasị ewu ewu n'etiti ụmụ akwụkwọ na-achọ enyemaka ọmụmụ a pụrụ ịdabere na ya.

Ọ bụ ezie na ọ nweghị ọmụmụ mmadụ banyere mmetụta ndị a kpọmkwem, ọmụmụ ụmụ anụmanụ na-egosi na pramiracetam na-enye aka na usoro ihe ọmụmụ na ncheta ncheta site na ịbawanye ụdị ọrụ nitric oxide synthase (NOS) na-arụ ọrụ na hippocampus. plasticity, nke ha bu ihe di nkpa na akuku cognition.

A maara Pramiracetam ka ọ na-eme ka njikọ dị elu dị elu na hippocampus, si otú a na-eme ka mmepụta nke acetylcholine, ihe dị mkpa nke na-emetụta ụbụrụ na cognition.

 

  • Ọgwụgwọ Dementia

Ihe nyocha a na-emeghe na ndị ọrịa nwere isi mgbaka na-egosi na Pramiracetam gbanwere amnesia n'ụzọ dị irè, na-eme ka ncheta dị elu ma belata nchefu.

N'ọmụmụ ihe ndị ọzọ, nke tụrụ mmetụta nke pramiracetam na ndị ọzọ racetam-klas nootropics na ndị ọrịa nwere nrịanrịa dị ala ma dị nro, enwere mmụba dị mma maka cognition na ebe nchekwa. Enwere ike ịkọwapụta nsonaazụ ndị a, opekata mpe n'akụkụ ụfọdụ, na mmelite nke nootropic nke ndị na-ahụ maka ntanetị.

Agbanyeghị na anabatabeghị pramiracetam dị ka ọgwụgwọ Alzheimer na US, edepụtara ya na Europe maka ọgwụgwọ nke mgbaka na nsogbu ndị ọzọ metụtara ọrịa Alzheimer na nsogbu ndị ọzọ na-arịa ọrịa akwara.

  • Ọnọdụ mmekọrịta mmadụ na ibe ya

Ọ bụ ezie na enweghị nyocha ederede banyere pramiracetam na mmekọrịta mmadụ na ibe ya, ọtụtụ ndị ọrụ na-akọ na ọ na-eme ka ha nwee mkparịta ụka na mmekọrịta mmadụ na ibe ya. Enwere ike ịkọwa mmetụta a, ma ọ dịkarịa ala akụkụ ụfọdụ, site na mmetụta mmetụta mmụọ mmetụta pramiracetam, isnke a na-akọwa mgbe ụfọdụ dị ka nke Ritalin. Mmetụta a nwere ike belata nchekasị nke ọha na eze ma, n'aka nke ya, mee ka mmekọrịta mmadụ na ibe ya dịkwuo mma.

 

  • Ike Neuroprotective

A maara Pramiracetam na ọ nwere mmetụta dị ukwuu na-emetụta neuroprotectant, nwere ike imeziwanye cognition na ụmụ mmadụ nwere ụbụrụ trauma.

Nnyocha egosila na ọ ga-enwe mmetụta na-enweghị atụ mgbe a na-eji ya eme ihe mgbe ịwa ahụ na-agwọ ọrịa na ọgwụgwọ ọrịa uche nke mmalite nke cerebrovascular.

 

Pramiracetam Ogwu onunu ogwu

Pramiracetam na-abịakarị n'ụdị ntụ, capsules emere tupu, ma ọ bụ mbadamba. Usersfọdụ ndị ọrụ na-akọ na ụdị ntụ ntụ nwere uto siri ike na-adịghị mma, yabụ na-ahọrọ iji ụdị capsule ma ọ bụ mbadamba ụrọ kama.

Dị ka ụfọdụ ndị na-eme nchọpụta si kwuo, ntụ ntụ na ụdị capsule nwere ike ịnweta ngwa ngwa ngwa ngwa karịa ụdị mbadamba. Agbanyeghị, ikike niile na ịdị ike niile ekwenyere na ha ga-adabara n ’ụdị dị iche iche.

N'ime otu ule ole na ole emegoro, ejiri ihe ngụkọta nke 1,200 mg mee ihe, kewaa ya na usoro 600-mg abụọ ma ọ bụ usoro 400-mg atọ gbasaa ụbọchị niile.

Dị ka onye so n'ezinụlọ racetam nke ọgwụ, pramiracetam kwenyere na ọ dabere na choline maka mmetụta ya, na iji ya nwere ike, ya mere, belata oke choline nke ahụ. N'ihi nke a, a na-atụ aro ya oge ụfọdụ ka ijikọta racetams na isi iyi nke choline, dịka alpha-GPC ma ọ bụ citicoline. Agbanyeghị, aro a dabere naanị na data sitere n'ọmụmụ anụmanụ, yabụ ekwesighi ịkọwa ya dị ka ụdị ndụmọdụ "ndị isi" ma ọ bụ "nke akwadoro ahụike".

 

Ozi di mkpa: Pramiracetam tojupụtara

Pramiracetam na-arụ ọrụ nke ọma n'onwe ya mana ọ nwekwara ike ịbụ onye nwere ikike dị ike maka ndị ọzọ nootropics, na-abawanye arụmọrụ ha. nootropic Nchịkọta.

Na-agbakwunye choline mgbakwunye na ngwugwu pramiracetam nwere ike inwe ọtụtụ elele. Ọ bụghị naanị na ọ nwere ike ịkwalite nsonaazụ pramiracetam, mana ọ nwekwara ike igbochi isi ọwụwa, nke bụkarị mmetụta a na-akọkarị. .

Maka ihe atụ 2 gbasara Pramiracetam nchịkọta:

 Pramiracetam na Oxiracetam Stack

Kwado pramiracetam nwere nkwalite ume dịka adrafinil ma ọ bụ oxiracetam nwere ike ime ka nchekwube nke uche sikwuo ike ma gbatị ya ogologo oge.

Pramiracetam na Aniracetam Stack

Kwado pramiracetam site na onye na-ahụ maka nchekasị dị ka aniracetam nwere ike inye ndị ọrụ nnukwu elebara anya na itinye uche n'ihe ma meziwanye ọnọdụ ma belata mmetụta nke iche echiche na nchekasị. Usersfọdụ ndị ọrụ na-ekwu na nchịkọta a na-akwalite ịkọwapụta mmekọrịta mmadụ na ibe ya ma melite ike ịrụ ọrụ ọha na eze.

 

Mmetụta Pramiracetam

A na-anabata Pramiracetam nke ọma ọbụna na nnukwu onunu ogwu, ọ bụkwa obere mmetụta mmetụta ole na ole ka edere.

Enwere ọtụtụ akụkọ na-adịghị adịkarị nke obere mmetụta na-agafe agafe, gụnyere isi ọwụwa, nhụjuanya nke eriri afọ, na mmetụta nke ụjọ ma ọ bụ mkpasu iwe.

Isi ọwụwa metụtara choline depletion bụ ahụkarị mmetụta nke racetam ụdị nootropics na enwere ike igbochi site na iji pramiracetam na njikọ na mgbakwunye choline.

Pramiracetam anaghị eri ahụ, ọ nweghịkwa mmetụta ọjọọ dị mkpa nke iji ogologo oge eme ihe. E nwere ihe akaebe na pramiracetam nwedịrị ike ịkwalite ahụike ụbụrụ yana weghachite ọrụ na ụbụrụ ụbụrụ.

 

Ebee ka Ebe Kachasị Mma Buyzụ Pramiracetam Online? 

Ezie na ọ bụ eziokwu na Piracetam bụ otu n'ime ihe ndị kasị ekwe nkwa nootropics, ọ bụ naanị ole na ole ọgwụ na ahụ ike na ọtụtụ n'ime ya, ma ọ bụrụ na ọ bụghị ụbọchị, bụ anụmanụ dabeere ọmụmụ na nnyocha. Uru dị oke mkpa nye ndị okenye nwere nsogbu isi mana ọ na-atụ aro ka ụmụaka na ndị okenye toro eto gbasara mkpa ha. Ọ dị mma iji ya rụọ ọrụ naanị mgbe ị na ndị ọzọ. nootropics.

E nwere ọtụtụ ebe nwere Piracetam maka ọrịre na ntanetị. Agbanyeghị, ọ kachasị mma ịzụta site na webụsaịtị nke na-agbaso ụkpụrụ dị mma n'ọhịa a. AASraw bụ onye na-ebugharị ntụkwasị obi nke nootropics, a na-emepụta ngwaahịa ha niile n'okpuru cGMP ma nwee ike nyochaa ogo ahụ n'oge ọ bụla, dịka anyị maara. Nwere ike ịtụle gbasara ha ma ọ bụrụ na ịchọrọ ịzụta Pramiracetam ntụ ntụ.

Enwere ike ịzụta ya n'aka onye ahịa a. Ha na-erere ogige ndị tụkwasịrị obi na CoA na ụgbọ mmiri zuru ụwa ọnụ. Dị ka ọgwụ ọ bụla ọzọ, ụfọdụ ụlọ ahịa nwere ike ịchọ ndenye ọgwụ tupu ịzụrụ. Piracetam ahịa nwekwara ike ịdị iche iche dabere na ọnọdụ.

 

Reference

[1] Ndị ọrụ, The Pink Sheet. Mee 27, 1991 Cambridge Neuroscience Developing Warner-Lambert's Pramiracetam

[2] Edere Ederede Orphan Orban na-akwadoghị na Ntinye Akaụntụ peeji nke August 2, 2015

[3] Drugs.com Drugs.com International ndepụta maka pramiracetam Page abanye August 2, 2015

[4] A Auteri et. al. Akwụkwọ akụkọ ụwa nke nyocha ọgwụ ọgwụ, 12 (3), 129-132 (1992-1-1)

[5] Ahụmahụ na ngwa nke pramistar, nkwadebe ọhụrụ nootropic, na ọgwụgwọ nke ncheta ncheta na ndị ọrịa nwere ọrịa ọrịa cerebrovascular. 2003 Dec.

[6] Ojiji nke ndị nootropic na ọgwụgwọ dị mgbagwoju anya nke ndị ọrịa nwere mgbagha nke ụbụrụ. 2008 Mee 30.

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