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Lorcaserin HCL ntụ ntụ

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AASraw nwere njikọ na mmepụta ikike site na gram ka usoro nchịkọta nke ntụ ntụ nke Lorcaserin HCL (1431697-94-7), n'okpuru ụkpụrụ CGMP na usoro nchịkwa mma.

Lorcaserin (1431697-94-7) HCL ntụ ntụ emetụta ụbụrụ na ụbụrụ na-achịkwa agụụ. Ọkụ na-eme ka ọ bụrụ na ị ga - ejiri nri dị nta.Lorcaserin hydrochloride ntụ ntụ na - eji nri na mmega ahụ na - emeso oke ibu.Lorcaserin hydrochloride ntụ ntụ na - eme mgbe ụfọdụ iji na - emeso oke ibu nke nwere ike ibute ọrịa shuga, cholesterol dị elu, ma ọ bụ ọbara mgbali elu .

Product Description

Volcanerin (1431697-94-7) video


Raw Lorcaserin (1431697-94-7) HCL ntụ ntụ bụ isi ihe na agwa

aha: Lorcaserin hydrochloride ntụ ntụ
CAS: 1431697-94-7
Molekụla Formula: C11H15Cl2N
Ọbara arọ: 232.1525
Melt Point: 212 ° C
Nchekwa Nche: -20 ℃
agba: White ntụ ntụ


Kedu ihe bụ Lorcaserin

Lorcaserin (CAS 1431697-94-7), na-ere ahịa n'okpuru aha aha bụ BELVIQ, ihe bụ isi bụ Nkọwa 846589-98-8 nke Lorcaserin HCL. FDA kwadoro HCL maka ụbụrụ maka ndị mmadụ buru oke ibu (nke nwere nchịkọta anụ ahụ, ma ọ bụ BMI, nke 30 ma ọ bụ karịa) ma ọ bụ ndị buru ibu (nke nwere BMI nke 27 ma ọ bụ n'elu) ma nwee ọ dịkarịa ala otu ọnọdụ ahụ ike metụtara ahụike dị ka ụdị ọrịa shuga 2, ọbara mgbali elu ma ọ bụ cholesterol dị elu.

Kedu ihe Lorcaserin ji mee

Ulo XCNUMX-846589 a na-akpọ Lorcaserin HCL, nọ na otu ọgwụ ndị a maara dịka ndị agonists na-anabata ọrịa serotonin. A na-eji Lorcaserin HCL tinyere nri na bodybuilding iji na-emeso oke ibu, n'ihi na abụba abụba. A na-enye ya mgbe ụfọdụ ka a na-emeso oke ibu nke metụtara cholesterol dị elu, ọbara mgbali elu, ma ọ bụ ụdị ọrịa shuga nke ụdị ọrịa 98. Ma Lorcaserin hydrochloride (Lorcaserin HCL) agaghị agwọ ọrịa ọ bụla (dịka ọrịa obi, ọrịa shuga, ọbara mgbali elu).

Usoro oru nke Lorcaserin

Ọkụ Lorcaserin hydrochloride na-arụ ọrụ site na ịchịkwa agụụ - kpọmkwem site na ịgbalite ụbụrụ nke ụbụrụ maka serotonin, ihe ntanetị nke na-eweta mmetụta nke satiety na afọ ojuju. A na-eji nri sitty center na-ebute ihe oriri, nke na-adị n'ime mkpụrụokwu ventromedial nke hypothalamus na ebe ndị agụụ na-anọ na hypothalamus n'akụkụ. Ihe ntinye dị iche iche site na ebe dị elu na tract gastrointestinal na-agbanye na ngwakọta ihe, ebe ụdị abụọ nke na-achịkwa nri oriri dị ugbu a. Mbụ, ihe oriri na-akpali agụụ mmekọahụ na-emepụta protein na protein neuropeptide Yuta; na nke abuo, otu oriri na-eri nri nke nwere cocaine na amphetamine na-edozi transcript (CART) na pro-opiomelanocortin (POMC) neurons. POMC nwere ihe nzaba 5-HT 2C, nke a na - eme ka a na - ebute hormone alpha-melanocyte (alfa-MSH) ma ọ bụrụ na a na - arụ ọrụ na - emepụta ihe ndị ọzọ na - emepụta ihe dị na hypothalamus.Utu nwere ike ịchọta ihe ndị na - anabata 4 (MC4R) nke na - na-eme ihe dịka onye agonist 5-HT 2C ahịrị na POMC neurons, nke nke a na-akpata ntọhapụ nke MSH alfa. Ihe ọzọ MSH MSH na-eme na MC4R na oghere paraventricular na hypothalamus, na-eme ka ọnụlata agụụ. Na nchịkwa supratherapeutic, lorcaserin na-emekwa na 5-HT 2B na ndị natara 5-HT 2A.

Otu esi eji ntụ ntụ Lorcaserin HCL (CAS 1431697-94-7)

Mkpụrụ mmanụ Lorcaserin HCL bụ ọcha na-acha ọcha na ntụ ntụ na solubility na mmiri karịrị 400 mg / ml. Nkpukpu BELVIQ XR nke ọ bụla nwere 20.8 mg nke crystalline lorcaserin hydrochloride hemihydrate, nke yiri 20.0 mg lorcaserin hydrochloride ntụ ntụ, na ihe na-esonụ arụ ọrụ: microcrystalline cellulose NF; mannitol USP; 2208 USP hypromellose; akpọrọ nke ethylcellulose Ụdị B NF; 2910 USP hypromellose; colloidal silicon dioxide NF; mmanya polyvinyl alcohol USP; polyethylene glycol NF; titanium dioxide USP; talc USP; FD & C edo edo # 6 / yellow FC yellow FCF; aluminum ọdọ; ígwè oxide odo NF; ígwè oxide acha uhie uhie NF; na magnesium stearate NF.

Akwukwo nke 846589-98-8 na-abịa na mbadamba ụrọ ma na-ewere 1-2 ugboro ugboro n'ụbọchị, na-enweghị nri. A ghaghị iji mpaghara a na-eji cacarie eme ihe na usoro ihe omumu.

Nkọwapụta mmekọrịta nke Lorcaserin

-monoamine oxidase inhibitors such as isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), selegiline (Emsam, Eldepryl, Zelapar), rasagiline (Azilect)

(SSD) dị ka escitalopin (Lexapro), sertraline (Zoloft), citalopram (Celexa), paroxetine (Paxil), fluoxetine (Prozac, Sarafem), na fluvoxamine (Luvox)

-tricyclic antidepressants dị ka trimipramine (Surmontil), amitriptyline (Elavil), nortriptyline (Pamelor, Aventyl), protriptyline (Vivactil), na clomipramine (Anafranil)


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COA

COA 1431697-94-7 Lorcaserin HCL ntụ ntụ AASraw

HNMR

Synphrine HCL ntụ ntụ (5985-28-4) hplc ma98% | AASraw suppliers

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20 ihe kachasị mkpa Ị ga-achọ ịma gbasara ọkụkọ Lorcaserin HCL